Fig. 1
From: Tumor-specific delivery of KRAS siRNA with iRGD-exosomes efficiently inhibits tumor growth
Characterization of the iRGD-exosomes loaded with KRAS siRNA. (a) Representative images of nanoparticles tracking analysis (NTA) indicating similar size distribution in diluted samples of HEK293T cells exosomes. (b) Representative western blot image of KRAS protein in A549 cells treated with wild type HEK293T exosomes (Mock), scrRNA-loading wild type exosomes (scrRNA/WT-exosome) or KRAS siRNA-loading iRGD-exosomes (siRNA-KRAS/iRGD-exosome). (c) Quantitative RT-PCR analysis of KRAS mRNA levels in A549 cells treated with mock exosomes, scrRNA/WT-exosomes or siRNA-KRAS/iRGD-exosomes. ***, p < 0.001