Table 2 Regulation of miRNA on metabolic pathways

miR-33

CPT1α

Lipid metabolism

[30, 31]

CROT

[30, 31, 34]

3-ketoacyl-coA thiolase

[31]

SIRT6

[37]

AMPKα1

[28, 55]

IRS2

[37]

miR-370

CPT1α

[32]

miR-142

[33]

miR-122

aldolase-A

[42]

miR-103, − 107

PANK

[45]

miR-224

ACSL4

[46]

miR-21

PPARα

[47, 48]

Mpv171

[47]

miR-17

PPARα

[49]

miR-105

MYC

[50]

miR-199a

PPARδ

[52]

miR-29a

[53]

miR-223

GLUT4

Glucose metabolism

[63]

miR-106a

GLUT3

[21, 69, 70]

miR-195-5p

[71]

miR-144

GLUT1

[72]

miR-1291

[73]

miR-328

[74]

miR-143

HK2

[75]

miR-155

STAT3

[76]

miR-124

[77]

miR-128

PFK

[78]

miR-320

[79]

miR-135

[80]

miR-200c

SIRT2

[81]

Let-7

PKM2, c-Myc

[82]

miR-326

PKM2

[83]

miR-133a, −133b

[84,85,86]

miR-122

[87]

miR-26a

PDHX

[89]

miR-34

LDHA

[90, 91]

miR-375

LDHB

[92,93,94]

miR-124

MCT1

[95]

miR-342-3p

[96]

miR-29

INSIG1, PI3K subunit p85α

Glycolytic related pathways

[59]

CAV2

[60, 61]

miR-126

IRS1

[62]

miR-103, −107

CAV1

[65]

miR-143

ORP 8

[67]

Let-7

IGF1R, IRS2

[68]

miR-340, − 124, − 137

hnRNPI, hnRNPA1, hnRNPA2

[88]

miR-410

c-Met

[97]

miR-144-3p

[98]

miR-34a

[99,100,101,102]

miR-34a

PDGFRA

[102]

miR-128

PDGFRA, EGFR

[103]

miR-219-5p

EGFR

[104, 105]

miR-7

[106, 107]

miR-9

NF1

[108]

miR-143

N-RAS

[109]

miR-340

[110, 111]

Let-7a

K-RAS

[112]

miR-134

[113]

miR-7

PI3K

[114]

miR-542-3p

Akt

[115]

miR-21

PTEN

[116]

miR-26a

[117]

miR-1908

[118]

miR-494-3p

[119]

miR-10a, −10b

[120]

miR-21, − 221

[121, 122]

miR-451

CAB39

[123, 124]

miR-199a-3p

mTORC1, mTORC2

[125]

miR-34a

Rictor

[101, 126]

miR-34c

c-Myc

[127]

miR-155

FoxO3a

[128]

miR-193b

SHMT2

Amino acid metabolism

[129]

miR-23a, 23b

Glutaminase

[130]

miR-29b

Digydrolipoyl branched chain acyltransferase

[131]

miR-1

ND1, COX1

Mitochondrial respiration and homeostasis

[135]

miR-181c

COX1

[140,141,142]

let7b, miR-146a, −133b, −106a, −19b, −20a, −34a, −181a, − 221

Bcl-1

[143, 144]

miR-378

ATP synthase

[145]

miR-1, −133a

Mef2A, Dik1-Dio3

[146]

miR-388

COX4

[147]

miR-210

ISCU, COX10

[148, 149]

SDHD

[150]

miR-355, −34a

SOD2, TR2

[151]

miR-25

NADPH oxidase

[152]

miR-26a

PDHX

[89]

miR-152, −148a, −148b, − 299, −19a, −19b, −122a, − 421, − 494

CS

[153]

miR-124

SUCLG2

[154]

miR-183

IDH

[155]

miR-743a

MDH

miR-15b, −16, − 195, − 424

ARL2

[156]

miR-30

p53

[158]

miR-26

UCP1

[159]

miR-27a, −27b

prohibitin

[160]

miR-149

PARP-1

[161]

miR-378

Caspase 3

[162]

miR-1

IGF

[163]