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Table 1 List of notable circRNAs and their roles in corresponding diseases

From: Circular RNA: functions, applications and prospects

DiseaseNotable TypesCircRNAFunctionReferences(PMID)
AgingPhotoagingcircCOL3A1-859267Regulates type I collagen expression10902104
CancerBreast cancerCirc-Foxo3Regulates cellular functioning of tissue cells14764598
15514005
14796821
Circ-ABCB10Sponges miR-127121566976
Colorectal cancerhsa_circ_100219Expressed due to differentiation and perineural invasion19492553
hsa_circ_001395817424658
hsa_circ_001988Overexpressed, potential biomarker19362625
hsa_circ_00156929973005
circ-BANP19506007
Gastric cancerCdr1asPlays antagonistic roles in regulating potential invasive liver cancer cells29969631
circPVT120452322
hsa_circ_10026918727980
circLARP413497006
Hepatocellular carcinomaCdr1asPotential marker 
circRNA_000839MicroRNA sponge13421335
circRNA_10033814230380
circZKSCAN120452322
Lung cancer Osteosarcomacirc-ITCHMicroRNA sponge18780261
circUBAP229805712
hsa_circ_001634728977896
hsa_circ_000991019492553
10902104
29255366
Pancreatic carcinomacircRNA_100782  
CardiovascularAtherosclerosisHas_circ_0003575Inhibited angiogenesis ability of HUVECs19506007
Myocardial infarctionCdr1asmiR-7a sponge19326203
DiabetesDiabetesCdr1asImproves insulin production by inhibiting miR-7a20452322
22128778
HepatopathyLiver fibrosishsa_circ_0071410MicroRNA sponge18790038
circRNA_021412
ImmuneInfectioncircRasGEF1BRegulates stability of mature ICAM-1 mRNA15558584
NeurologicalAlzheimer’s diseaseCdr1asSponges miRNA-716648021
Diabetic retinopathycircHIPK3Inhibits miR-124 activity00652598
20411723
Parkinson’s diseaseCdr1asSponges miRNA-727147959
Skin, muscle and boneOsteoarthritiscircRNA-CERPromotes the degradation of chondrocyte ECM20452322
circRNA-MSR21622531
circRNA_Atp9b18790038