Fig. 2

Relative expression of miR-19a, miR-143 and miR-374-5p in the different AP groups. Serum concentrations of three miRNAs were measured in 45 MAP patients, 42 MSAP patients, 38 SAP patients and 52 healthy control individuals (HCs) (in both the training and validation sets) with qRT-PCR. The expression of miR-19a (a), miR-143 (b) and miR-374-5p (c) were significantly different among all paired groups (p < 0.05). Each point represents the mean results for triplicate samples. The middle bars represent the mean and whiskers SEM. Cq values were converted to relative expressions with normalization to MIR2911. One-way ANOVA followed by the LSD test was performed after the data were transformed by natural logarithm. * p < 0.05; ** p < 0.01; *** p < 0.001