Secretory and circulating bacterial small RNAs: a mini-review of the literature

ExRNA

Table 1 A summary of the reviewed studies on secretory bacterial sRNAs

Origin	Secretion	Remark	Reference
Escherichia coli substrain MG1655	OMVs	The first detailed study on the secretory sRNA of Escherichia coli	[15]
Vibrio cholerae	OMVs	Transcribed from intergenic regions	[16]
Pseudomonas aeruginosa	OMVs	sRNA52320 targets host’s immune response gene	[17]
Uropathogenic Escherichia coli strain 536	OMVs	sRNAs can be transferred into epithelial cells	[18]
Group A Streptococcus	MVs	From Gram-positive bacteria, miRNA-sized	[21]
Streptococcus sanguinis	MVs	From Gram-positive bacteria, miRNA-sized	[25]
Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and Treponema denticola	OMVs	From periodontal pathogens, miRNA-sized	[19]
Salmonella	Undetermined	Sal-1 targets iNOS in a miRNA-like manner	[26, 27]
Phylum Firmicutes	Circulation	Gut microbiome	[38]
Genera Escherichia and Acinetobacter	Circulation	Gut microbiome	[39]
Phylum Proteobacteria	Circulation	Gut microbiome	[36]
Mycobacterium tuberculosis	Culture supernatant and circulation	ASdes is detectable in the plasma from active tuberculosis patients	[41]

ISSN: 2398-0060