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Table 3 Cytokine concentrations in culture media of PBMCs isolated before and after a milk meal in healthy adultsa

From: MicroRNAs in bovine milk exosomes are bioavailable in humans but do not elicit a robust pro-inflammatory cytokine response

Cytokine

Hours

Pre-milk meal (pg/mL)

Post-milk meal (pg/mL)

IL-2

24

2 ± 0.6

3 ± 1.6

48

4 ± 1.4

5 ± 1.9

72

1 ± 0.3

1 ± 0.15

IL-4

24

5 ± 1.1

6 ± 1.1

48

5 ± 1.3

6 ± 1.4

72

3 ± 0.7

3 ± 0.6

IL-5

24

4 ± 0.9

4 ± 1.8

48

4 ± 1.0

4 ± 1.1

72

1 ± 0.2

1 ± 0.1

IL-17A

24

3 ± 0.7

5 ± 2.1

48

13 ± 0.9

13 ± 8.8

72

1 ± 0.1

4 ± 3.1

IFN-γ

24

3 ± 0.8

4 ± 1.2

48

3 ± 0.7

4 ± 1.3

72

1 ± 0.2

1 ± 0.4

  1. aValues are means ± SEM, n = 12 p > 0.05 for PBMCs collected before vs. after milk consumption and treated with ConA for 24, 48 and 72 h. ConA Concanavalin A, IFN-γ Interferon-gamma, IL interleukin