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Table 1 Terminologies related to isomiRs

From: Biogenesis and biological implications of isomiRs in mammals- a review

S.No IsomiR name Description*
1 5′ isomiR Base change (deletion or addition) at 5′ terminus
2 3′ isomiR Base change (deletion or addition) at 3′ terminus
3 RC Read count (used for NGS read counts after sequencing transcriptome or sRNA)
4 UR Unique reads of a particular miRNA or isomiR or transcript
5 3SNE Single nucleotide extension in 3′ end
6 3MNE Multiple nucleotide extension in 3′ end
7 3Trim the read is shorter than the reference mature sequence but it starts at the same position in the hairpin
8 5MNE Multiple nucleotide extension in 5′ end
9 5Trim the read aligns to a position in the hairpin after the reference mature sequence BUT the last base of the read and the mature sequence map to the same position
10 Mature star Less expressed arm of the pre-miRNA
11 Predom UR the number of unique reads of the predominant mature microRNA sequence
12 Predom RC the read count of the predominant mature microRNA sequence
13 Star RC the read count of the predominant mature microRNA sequence
14 Star UR the number of unique reads of the predominant mature microRNA sequence
15 IsoRC IsomiR read count
16 Exact RC the read count of perfectly mapped miRBase consensus sequences
17 3SNA Single nucleotide addition in 3′
18 3 MNA Multiple nucleotide addition in 3′
19 RPM Reads per Millions
20 Other LV The number of other length variants (those that have length variation in 5′ and 3′)
  1. *Table source: https://bioinfo2.ugr.es/miRanalyzer/miRanalyzer_tutorial.html