Table 1 Terminologies related to isomiRs
From: Biogenesis and biological implications of isomiRs in mammals- a review
S.No | IsomiR name | Description* |
|---|---|---|
1 | 5′ isomiR | Base change (deletion or addition) at 5′ terminus |
2 | 3′ isomiR | Base change (deletion or addition) at 3′ terminus |
3 | RC | Read count (used for NGS read counts after sequencing transcriptome or sRNA) |
4 | UR | Unique reads of a particular miRNA or isomiR or transcript |
5 | 3SNE | Single nucleotide extension in 3′ end |
6 | 3MNE | Multiple nucleotide extension in 3′ end |
7 | 3Trim | the read is shorter than the reference mature sequence but it starts at the same position in the hairpin |
8 | 5MNE | Multiple nucleotide extension in 5′ end |
9 | 5Trim | the read aligns to a position in the hairpin after the reference mature sequence BUT the last base of the read and the mature sequence map to the same position |
10 | Mature star | Less expressed arm of the pre-miRNA |
11 | Predom UR | the number of unique reads of the predominant mature microRNA sequence |
12 | Predom RC | the read count of the predominant mature microRNA sequence |
13 | Star RC | the read count of the predominant mature microRNA sequence |
14 | Star UR | the number of unique reads of the predominant mature microRNA sequence |
15 | IsoRC | IsomiR read count |
16 | Exact RC | the read count of perfectly mapped miRBase consensus sequences |
17 | 3SNA | Single nucleotide addition in 3′ |
18 | 3 MNA | Multiple nucleotide addition in 3′ |
19 | RPM | Reads per Millions |
20 | Other LV | The number of other length variants (those that have length variation in 5′ and 3′) |