Altered human cytomegalovirus-encoded miRNAs in host circulation: novel disease biomarkers and potential aetiological agents

ExRNA

Table 2 Differential expression of circulating HCMV-encoded miRNAs under various disease conditions

HCMV-encoded miRNA	Sample type	Diseases	Alteration	References
hcmv-miR-UL112	Plasma	Essential hypertension	Upregulation	[32]
	Plasma	Type 2 diabetes	Upregulation	[81]
	Plasma	Glioblastoma	Upregulation	[81]
hcmv-miR-US5-1, hcmv-miR-US-5-2-3p, hcmv-miR-UL-22a-5p, hcmv-miR-US25-1-5p, hcmv-miR-US-25-2-3p, hcmv-miR-US-25-2-5p, hcmv-miR-US-33-3p, hcmv-miR-UL36-5p, hcmv-miR-UL112-3p	Blood	Solid organ transplantation	Upregulation	[83]
hcmv-miR-US25-1-5p, hcmv-miR-US25-2-5p	Plasma	Congenital CMV infection	Upregulation	[84]
hcmv-miR-US33-5p	Plasma	Acute aortic dissection	Upregulation	[86]
hcmv-miR-US4-1, hcmv-miR-UL-148D	Serum	IFNα treatment non-responsive chronic hepatitis B	Upregulation	[87]
hcmv-miR-UL112-3p, hcmv-miR-UL22a-5p, hcmv-miR-UL148d, hcmv-miR-UL36-5p, hcmv-miR-UL59	Serum	Oral lichen planus	Upregulation	[35]

ISSN: 2398-0060