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Table 1 Patient characteristicsa

From: Serum microRNAs as novel biomarkers for early prediction of disease severity in patients with acute pancreatitis

 

HCs (n = 52)

(n = 45)

MSAP (n = 42)

SAP (n = 38)

p

Age (years)

47.4 (17.1)

42.3 (16.9)

48.1 (15.8)

44.6 (14.7)

0.835b

Male (% total)

32 (61.5)

29 (64.3)

27 (64.3)

22 (57.9)

0.923c

Etiology (% total)

0.037c

 Gallstones

22 (48.9)

17 (40.5)

19 (50.0)

 Hyperlipidemia

15 (33.3)

13 (31.0)

18 (47.4)

 Alcohol misuse

3 (7.1)

 Other

8 (17.8)

12 (28.6)

1 (2.6)

WBC (× 109/L)d, e, f

6.0 (1.5)

10.6 (4.0)

13.0 (5.5)

13.4 (5.5)

< 0.001b

CRP (mg/L)d, e, f, g, h

2.7 (2.4)

39.5 (53.6)

97.3 (83.1)

135.0 (79.3)

< 0.001b

SGOT (U/L)d, e, f

20.7 (4.6)

93.8 (170.5)

120.4 (190.3)

125.0 (166.0)

< 0.001b

BUN (mmol/L)

5.0 (1.0)

12.1 (48.0)

4.8 (2.1)

6.8 (6.5)

0.245b

Serum creatinine (μmol/L)

55.7 (11.1)

60.7 (19.0)

60.6 (16.7)

71.7 (55.8)

0.492b

Ranson scored, e, f, g, h, i

0.4 (0.5)

1.1 (1.0)

1.9 (1.2)

3.0 (1.4)

< 0.001b

APACHE IIe, f, g, h

1.7 (1.7)

2.4 (2.0)

4.2 (2.5)

6.2 (3.9)

< 0.001b

Length of stay (days)h, i

9.2 (3.2)

10.2 (4.5)

18.7 (10.7)

< 0.001b

ICU admission (% total)h, i

25 (55.6)

31 (73.8)

37 (97.4)

< 0.001c

Length of ICU stay (days)h, i

2.2 (2.8)

3.7 (3.7)

10.7 (6.7)

< 0.001b

Need for intervention

2

27

 Surgical

1

 Interventional

2

15j

 Supportive

 

21j

Mortality

1

  1. aData are mean (SD) or number (%).bKruskal-Wallis Test.cFisher’s Exact Test.d-iMann-Whitney U test:dp < 0.008 between the HCand MAP groups; ep < 0.008 between the HC and MSAP groups; fp < 0.008 between the HC and SAP groups; gp < 0.008 between the MAP and MSAP groups; hp < 0.008 between the MAP and SAP groups;ip < 0.008 between the MSAP and SAP groups. j10 patients needed both interventional and supportive intervention. HC Healthy controls, MAP Mild acute pancreatitis, MSAP Moderately severe acute pancreatitis, SAP Severe acute pancreatitis, WBC White blood count, CRP C-reactive protein, SGOT Serum glutamic oxaloacetic transaminase, BUN Blood urea nitrogen, APACHE II Acute Physiology and Chronic Health Evaluation II