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Since the discovery of the stability of extracellular microRNAs (miRNAs) in plasma and other body fluids about a decade ago, an increasing body of literature has addressed the function of extracellular miRNAs ...
MicroRNA (miRNA) dysregulation is causal in most, if not all, cancers. They silence the gene’s expression by modulating messenger RNA (mRNA) through employing translational repression or degradation. MiRNA has...
Intracellular target identification of microRNA (miRNA), which is essential for understanding miRNA-involved cellular processes, is currently the most challenging task in miRNA-related studies. Although bioinf...
The discovery of extracellular RNA (exRNA) in blood and bodily fluids has expended our knowledge on RNA functions. ExRNAs may be transferred between cells and have functional significance in health and disease...
IsomiRs, the sequence-variants of microRNA (miRNA), are characterized by variation at the 3′- and/or 5′-end(s) of canonical miRNA-sequence as a result of nucleotide addition or deletion or substitution. These ...
Hepatitis E (HE) is prevalent in developing countries in both epidemic and sporadic forms and is characterized by high mortality during pregnancy. miR-122, the major hepatic microRNA has been shown to be modul...